SLCO1B3-SLCO1B7

Across TCGA patient cohorts, SLCO1B3-SLCO1B7 protein abundance is significantly associated with the RNA expression of many other genes, with 435 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLCO1B3-SLCO1B7-associated genes across cancer lineages are GGT1, PRODH, and C22orf31. Each is linked with SLCO1B3-SLCO1B7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLCO1B3-SLCO1B7-to-partner and partner-to-SLCO1B3-SLCO1B7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLCO1B3-SLCO1B7 versus GGT1 in BRCA, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLCO1B3-SLCO1B7→partner) and Y-score (partner→SLCO1B3-SLCO1B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GGT1 →	+1.954	+2.951	<.001	.007	3	1
BRCA	PRODH →	+1.754	+1.812	<.001	.008	3	1
BRCA	C22orf31 →	+0.357	+1.800	<.001	.008	3	1
BRCA	SLC10A1 →	+0.344	+1.915	<.001	.003	3	1
BRCA	RPS10P5 →	+1.406	+2.920	.009	.003	3	1
BRCA	TSC22D1 →	+1.540	+3.102	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 435 associations by consensus.

SLCO1B3-SLCO1B7 vs GGT1 — BRCA

Explore this scatter interactively →