SLC5A5

Across TCGA patient cohorts, SLC5A5 mutation is significantly associated with the RNA expression of many other genes, with 1,697 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A5-associated genes across cancer lineages are IGHD4-4, COPS5P1, and RNU6-453P. Each is linked with SLC5A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC5A5-to-partner and partner-to-SLC5A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD4-4 grouped by SLC5A5-low versus SLC5A5-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A5→partner) and Y-score (partner→SLC5A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	IGHD4-4 →	+1.466	+5.039	<.001	.008	3	3
BRCA	COPS5P1 →	+0.081	+4.278	<.001	.008	3	3
STAD	RNU6-453P →	+1.059	+3.646	<.001	.009	3	3
SKCM	SNORA80C →	+0.219	+1.828	.003	.008	3	3
STAD	RNU6-246P →	+0.606	+3.782	<.001	.007	3	3
SKCM	MIR933 →	+0.776	+2.549	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,697 associations by consensus.

IGHD4-4 by SLC5A5 expression — READ

Explore this box plot interactively →