SLC4A11

Across TCGA patient cohorts, SLC4A11 mutation is significantly associated with the RNA expression of many other genes, with 5,679 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A11-associated genes across cancer lineages are TIMM44, CEP55, and MIR6736. Each is linked with SLC4A11 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC4A11-to-partner and partner-to-SLC4A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMM44 grouped by SLC4A11-low versus SLC4A11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A11→partner) and Y-score (partner→SLC4A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMM44 →	+0.388	+1.710	<.001	<.001	3	4
UCEC	CEP55 →	+0.647	+1.494	<.001	.001	3	4
SKCM	MIR6736 →	+0.201	+1.607	.004	.009	3	3
UCEC	SENP3-EIF4A1 →	+0.112	+1.938	<.001	<.001	3	3
UCEC	MIR4672 →	+0.292	+1.468	<.001	.003	3	3
SKCM	TSPY26P →	-0.968	-3.756	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,679 associations by consensus.

TIMM44 by SLC4A11 expression — UCEC

Explore this box plot interactively →