SLC49A4

Across TCGA patient cohorts, SLC49A4 mutation is significantly associated with the RNA expression of many other genes, with 1,011 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC49A4-associated genes across cancer lineages are GSTA12P, VDAC2P4, and LINC01069. Each is linked with SLC49A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC49A4-to-partner and partner-to-SLC49A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSTA12P grouped by SLC49A4-low versus SLC49A4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC49A4→partner) and Y-score (partner→SLC49A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	GSTA12P →	+0.313	+5.201	<.001	.007	3	2
CESC	VDAC2P4 →	+0.086	+5.010	<.001	.009	3	2
CESC	LINC01069 →	+0.078	+6.837	<.001	<.001	3	2
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	1
UCEC	PGAP2 →	+0.445	+3.711	.007	<.001	3	1
UCEC	CPSF7 →	+0.435	+3.202	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,011 associations by consensus.

GSTA12P by SLC49A4 expression — CESC

Explore this box plot interactively →