Q-omics provides the consensus-scored GSTA12P profile across patient tissues and cancer cell-line models. GSTA12P expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, GSTA12P is differentially expressed in 4, with the highest sampling consensus in HNSC. Additionally, GSTA12P RNA expression shows 8,860 significant gene co-expression associations, with the highest sampling consensus in LIHC. Together, these results highlight UCEC, HNSC, and LIHC as cancer lineages where GSTA12P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GSTA12P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GSTA12P survival associations across molecular data types. GSTA12P RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GSTA12P RNA expression–survival associations across cancer types. High GSTA12P expression shows unfavorable associations in UCEC, KICH, LAML and READ, but favorable associations in BLCA and LIHC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for GSTA12P RNA expression.
This table summarizes GSTA12P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for GSTA12P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GSTA12P shows lower tumor expression in CHOL and LIHC and higher tumor expression in HNSC and LUSC. The HNSC box plot shows higher GSTA12P RNA expression in tumor versus normal tissue (log2 FC = +0.109, t-test p = .018).
This table shows molecular features associated with GSTA12P in patient tissues and cancer cell lines. In patient samples, GSTA12P shows the broadest associations at the RNA and protein expression levels, with LIHC recurring as the lineage with the largest associated feature set.
