SLC38A5

Across TCGA patient cohorts, SLC38A5 mutation is significantly associated with the RNA expression of many other genes, with 2,724 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC38A5-associated genes across cancer lineages are RNU5A-2P, RPSAP68, and CDH12P1. Each is linked with SLC38A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC38A5-to-partner and partner-to-SLC38A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5A-2P grouped by SLC38A5-low versus SLC38A5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A5→partner) and Y-score (partner→SLC38A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU5A-2P →	+0.461	+5.112	<.001	.004	3	3
BRCA	RPSAP68 →	+0.063	+6.234	<.001	<.001	3	2
SKCM	CDH12P1 →	+0.083	+4.199	<.001	.009	3	2
BRCA	MIR548AD →	+0.316	+8.471	<.001	<.001	3	2
CESC	MRGPRX8P →	+0.022	+5.263	<.001	.001	3	2
BRCA	RPL17P12 →	+0.090	+5.382	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,724 associations by consensus.

RNU5A-2P by SLC38A5 expression — BRCA

Explore this box plot interactively →