SLC35B3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC35B3 mutation is significantly associated with the RNA expression of many other genes, with 3,225 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC35B3-associated genes across cancer lineages are RNU1-18P, RN7SL248P, and MIR6780B. Each is linked with SLC35B3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC35B3-to-partner and partner-to-SLC35B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-18P grouped by SLC35B3-low versus SLC35B3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC35B3→partner) and Y-score (partner→SLC35B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU1-18P →+0.324+6.147<.001.00232
UCECRN7SL248P →+0.068+3.307<.001.00332
UCECMIR6780B →+0.291+2.404<.001.00432
READNPLP1 →+0.291+5.421<.001.00532
COADMIR4298 →+1.615+5.790<.001.00332
LUADOR8F1P →+0.147+5.554<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,225 associations by consensus.

RNU1-18P by SLC35B3 expression — BLCA

Box plot of RNU1-18P in SLC35B3-low vs SLC35B3-high samples in BLCA.

Explore this box plot interactively →

Exploration