SLC25A32

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A32 mutation is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A32-associated genes across cancer lineages are RNU6-203P, MIR193B, and HLTF-AS1. Each is linked with SLC25A32 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A32-to-partner and partner-to-SLC25A32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-203P grouped by SLC25A32-low versus SLC25A32-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A32→partner) and Y-score (partner→SLC25A32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNU6-203P →+0.237+5.649<.001.00132
BRCAMIR193B →+0.436+4.231<.001.00332
LUADHLTF-AS1 →+0.125+6.315<.001.00132
STADSNORD3H →+0.308+4.363<.001.00732
UCECRNA5SP248 →+0.365+2.557.001.00132
UCECRNU6-994P →+0.243+3.716<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

RNU6-203P by SLC25A32 expression — BRCA

Box plot of RNU6-203P in SLC25A32-low vs SLC25A32-high samples in BRCA.

Explore this box plot interactively →

Exploration