HLTF-AS1

Q-omics provides the consensus-scored HLTF-AS1 profile across patient tissues and cancer cell-line models. HLTF-AS1 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in OV. Additionally, HLTF-AS1 RNA expression shows 6,208 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight OV, and STAD as cancer lineages where HLTF-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes HLTF-AS1 survival associations across molecular data types. HLTF-AS1 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

HLTF-AS1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	OV (108)	view →

This table ranks reproducible HLTF-AS1 RNA expression–survival associations across cancer types. High HLTF-AS1 expression shows unfavorable associations in SKCM, LIHC, KIRC, PCPG and LGG, but favorable associations in OV. The OV Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .005). Together, the overview and detailed table identify OV as the clearest survival context for HLTF-AS1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	III,IV	0.337	0.140	.005	108	view →
SKCM	OS	Tertile	All	0.439	0.792	<.001	93	view →
LIHC	OS	Tertile	All	0.447	0.783	<.001	81	view →
KIRC	OS	Tertile	All	0.497	0.654	.005	40	view →
PCPG	DFS	Tertile	All	0.086	0.768	.007	18	view →
LGG	DFS	Tertile	All	0.511	0.746	.044	15	view →

Pink = unfavorable, green = favorable. all 8 lineages →

HLTF-AS1-OV (DFS)

Explore this curve interactively →