Q-omics provides the consensus-scored SNORD3H profile across patient tissues and cancer cell-line models. SNORD3H expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, SNORD3H is differentially expressed in 2, with the highest sampling consensus in CHOL. Additionally, SNORD3H RNA expression shows 6,302 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight ACC, CHOL, and COAD as cancer lineages where SNORD3H shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNORD3H — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNORD3H survival associations across molecular data types. SNORD3H RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNORD3H RNA expression–survival associations across cancer types. High SNORD3H expression shows unfavorable associations in ACC, BLCA, HNSC, LUAD, OV and KIRC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for SNORD3H RNA expression.
This table summarizes SNORD3H tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in CHOL for RNA.
This table ranks reproducible tumor–normal expression differences for SNORD3H. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNORD3H shows lower tumor expression in CHOL and higher tumor expression in LIHC. The CHOL box plot shows higher SNORD3H RNA expression in normal versus tumor tissue (log2 FC = −0.375, t-test p = .004).
This table shows molecular features associated with SNORD3H in patient tissues and cancer cell lines. In patient samples, SNORD3H shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
