SLC25A20

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC25A20 mutation is significantly associated with the RNA expression of many other genes, with 1,398 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A20-associated genes across cancer lineages are UBTFL10, MIR4445, and AK4P5. Each is linked with SLC25A20 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A20-to-partner and partner-to-SLC25A20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBTFL10 grouped by SLC25A20-low versus SLC25A20-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A20→partner) and Y-score (partner→SLC25A20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAUBTFL10 →+0.739+5.016<.001.00533
UCECMIR4445 →+0.215+4.777<.001.00232
SKCMAK4P5 →+0.040+4.993<.001.00232
UCECRNU6-806P →+0.232+3.335<.001.00432
BRCARN7SL248P →+0.103+5.786<.001.00131
CESCCRLF3P1 →+0.034+4.984<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,398 associations by consensus.

UBTFL10 by SLC25A20 expression — BRCA

Box plot of UBTFL10 in SLC25A20-low vs SLC25A20-high samples in BRCA.

Explore this box plot interactively →

Exploration