SLC25A20

Across TCGA pan-cancer cohorts, SLC25A20 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SLC25A20 data layer compared with 3 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLC25A20 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC25A20 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SARC show a favorable association.

KIRC, KICH, and ACC are the cancer types where SLC25A20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.726	0.519	<.001	90	view →
KICH	DFS	Median	II,III,IV	0.677	1.000	.001	85	view →
ACC	DFS	Median	All	0.231	0.656	<.001	67	view →
LGG	OS	Median	All	0.740	0.872	<.001	47	view →
SARC	DFS	Median	All	0.692	0.525	<.001	38	view →
BRCA	OS	Median	III,IV	0.660	0.401	<.001	30	view →
LUAD	DFS	Median	II,III,IV	0.801	0.635	.005	16	view →
COAD	OS	Quartile	IV	0.799	0.352	.007	15	view →
KIRP	OS	Median	II,III,IV	0.875	0.661	.014	15	view →
SKCM	DFS	Median	III,IV	0.465	0.812	<.001	13	view →
ESCA	OS	Median	All	0.563	1.000	.003	12	view →
READ	OS	Quartile	IV	0.489	1.000	.023	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SLC25A20–KIRC (DFS)

Open the KIRC breakdown →