SLC25A2

Across TCGA patient cohorts, SLC25A2 protein abundance is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A2-associated genes across cancer lineages are CASC3, KLHDC7B, and NFATC1. Each is linked with SLC25A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A2-to-partner and partner-to-SLC25A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A2 versus CASC3 in UCEC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A2→partner) and Y-score (partner→SLC25A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CASC3 →	-0.605	-0.612	.008	.005	3	1
UCEC	KLHDC7B →	-0.649	-0.628	.001	.003	3	1
UCEC	NFATC1 →	-0.851	-0.418	.008	.009	3	1
UCEC	RUBCN →	-0.579	-0.833	.007	.006	3	1
UCEC	FOXA3 →	+1.776	+0.628	<.001	.005	3	1
UCEC	FCGR3A →	-1.388	-0.841	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

SLC25A2 vs CASC3 — UCEC

Explore this scatter interactively →