SLC1A4

Across TCGA patient cohorts, SLC1A4 mutation is significantly associated with the RNA expression of many other genes, with 1,392 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC1A4-associated genes across cancer lineages are RNA5SP457, MIR4743, and ELOCP5. Each is linked with SLC1A4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC1A4-to-partner and partner-to-SLC1A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP457 grouped by SLC1A4-low versus SLC1A4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A4→partner) and Y-score (partner→SLC1A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP457 →	+0.465	+3.792	.007	.007	3	3
LGG	MIR4743 →	+0.337	+6.363	<.001	.001	3	2
BRCA	ELOCP5 →	+0.096	+8.057	<.001	.005	3	2
LUSC	RNU6-1313P →	+0.267	+4.606	<.001	.006	3	2
BRCA	RNU6-821P →	+0.598	+5.317	<.001	.006	3	2
BRCA	RN7SKP221 →	+0.105	+7.471	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,392 associations by consensus.

RNA5SP457 by SLC1A4 expression — COAD

Explore this box plot interactively →