SLBP

Across TCGA patient cohorts, SLBP RNA expression is significantly associated with the protein abundance of many other proteins, with 11,450 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLBP-associated proteins across cancer lineages are RFC2, SMC2, and RFC4. Each is linked with SLBP in more than 8 cancer types. Because this analysis shows association rather than direction, both SLBP-to-partner and partner-to-SLBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLBP versus RFC2 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLBP→partner) and Y-score (partner→SLBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.397	+0.659	.001	<.001	3	9
GBM	SMC2 →	+0.675	+0.459	<.001	.002	3	9
LSCC	RFC4 →	+0.440	+0.661	.002	<.001	3	8
BRCA	NCAPG →	+0.567	+0.541	<.001	<.001	3	8
GBM	SMC4 →	+0.637	+0.503	.001	<.001	3	8
OV	RFC1 →	+0.427	+0.893	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,450 associations by consensus.

SLBP vs RFC2 — LSCC

Explore this scatter interactively →