SLBP

Across TCGA pan-cancer cohorts, SLBP RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLBP’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLBP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLBP is over-expressed in tumor.

HNSC, BLCA, and LUAD are the cancer types where SLBP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLBP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.907	<.001	12	view →
BLCA	Male	III,IV	+0.979	<.001	11	view →
LUAD	Male	All	+0.800	<.001	11	view →
LIHC	Male	II,III,IV	+1.368	<.001	9	view →
COAD	Female	II,III,IV	+0.964	<.001	9	view →
STAD	Male	II,III,IV	+1.140	<.001	8	view →
LUSC	Female	All	+1.071	<.001	7	view →
UCEC	All	III,IV	+0.772	.008	6	view →
BRCA	All	III,IV	+0.666	<.001	6	view →
THCA	Male	All	+0.301	<.001	6	view →
CHOL	All	All	+1.974	<.001	5	view →
ESCA	All	All	+0.959	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLBP–HNSC

Open the HNSC breakdown →