SH3TC2-DT

Across TCGA patient cohorts, SH3TC2-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 10,797 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3TC2-DT-associated proteins across cancer lineages are DOCK9, MYO18A, and SAMD9. Each is linked with SH3TC2-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both SH3TC2-DT-to-partner and partner-to-SH3TC2-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3TC2-DT versus DOCK9 in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3TC2-DT→partner) and Y-score (partner→SH3TC2-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DOCK9 →	+0.287	+0.391	<.001	<.001	3	5
HNSC	MYO18A →	+0.324	+0.519	<.001	<.001	3	4
LSCC	SAMD9 →	+0.589	+0.488	<.001	<.001	3	4
BRCA	UACA →	+0.224	+0.182	.004	.001	3	3
LUAD	SERPINB5 →	+1.455	+0.117	<.001	.002	3	3
GBM	PCDH1 →	+0.370	+0.541	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,797 associations by consensus.

SH3TC2-DT vs DOCK9 — GBM

Explore this scatter interactively →