SDHAF4

Across TCGA patient cohorts, SDHAF4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,649 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SDHAF4-associated genes across cancer lineages are IRF8, RASGRF2, and ETV1. Each is linked with SDHAF4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SDHAF4-to-partner and partner-to-SDHAF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDHAF4 versus IRF8 in COAD, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHAF4→partner) and Y-score (partner→SDHAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IRF8 →	-1.096	-0.609	<.001	.002	3	4
UCEC	RASGRF2 →	-0.830	-0.498	<.001	<.001	3	3
UCEC	ETV1 →	-0.935	-0.422	<.001	<.001	3	3
LSCC	CD79A →	-1.353	-0.417	<.001	.003	3	3
HNSC	SLC17A5 →	+0.573	+0.325	<.001	<.001	3	3
GBM	KCNK1 →	+1.469	+0.366	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,649 associations by consensus.

SDHAF4 vs IRF8 — COAD

Explore this scatter interactively →