SDCBP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SDCBP2 mutation is significantly associated with the RNA expression of many other genes, with 1,361 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDCBP2-associated genes across cancer lineages are MTND3P16, RNU6-839P, and RNA5SP419. Each is linked with SDCBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDCBP2-to-partner and partner-to-SDCBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND3P16 grouped by SDCBP2-low versus SDCBP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDCBP2→partner) and Y-score (partner→SDCBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMTND3P16 →+0.240+5.199<.001.00332
BRCARNU6-839P →+0.274+8.471<.001.00532
UCECRNA5SP419 →+0.632+2.424<.001.00132
COADMIR4667 →+0.753+3.681<.001.00932
STADLINC02477 →+0.491+3.723<.001.00632
BRCAMIR8062 →+0.592+8.471<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,361 associations by consensus.

MTND3P16 by SDCBP2 expression — SKCM

Box plot of MTND3P16 in SDCBP2-low vs SDCBP2-high samples in SKCM.

Explore this box plot interactively →

Exploration