SDCBP2

Across TCGA pan-cancer cohorts, SDCBP2 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SDCBP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SDCBP2 RNA is repressed in tumor relative to normal tissue. In most cancer types SDCBP2 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

COAD, KICH, and READ are the cancer types where SDCBP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SDCBP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−2.460	<.001	12	view →
KICH	Female	II,III,IV	+2.830	<.001	8	view →
READ	All	All	−2.961	<.001	7	view →
CHOL	All	All	+2.510	<.001	5	view →
THCA	All	All	−0.358	.002	5	view →
LUAD	All	II,III,IV	+0.941	.001	4	view →
KIRP	All	All	−0.672	.002	4	view →
KIRC	All	II,III,IV	−0.376	.006	3	view →
PAAD	All	All	+2.507	.044	2	view →
PRAD	All	All	−0.759	<.001	2	view →
LIHC	Female	All	+0.915	.043	1	view →
LUSC	All	All	+0.476	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

SDCBP2–COAD

Open the COAD breakdown →