long intergenic non-protein coding RNA 2477Genealiases: []
Q-omics provides the consensus-scored LINC02477 profile across patient tissues and cancer cell-line models. LINC02477 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, LINC02477 is differentially expressed in 8, with the highest sampling consensus in HNSC. Additionally, LINC02477 RNA expression shows 6,723 significant protein co-abundance associations, with the highest sampling consensus in PDAC. Together, these results highlight BRCA, HNSC, and PDAC as cancer lineages where LINC02477 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02477 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02477 survival associations across molecular data types. LINC02477 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02477 RNA expression–survival associations across cancer types. High LINC02477 expression shows unfavorable associations in BRCA, UCEC, KIRP, LUAD and HNSC, but favorable associations in ACC. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify BRCA as the clearest survival context for LINC02477 RNA expression.
This table summarizes LINC02477 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02477. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02477 shows lower tumor expression in KICH, KIRC and KIRP and higher tumor expression in HNSC, LUAD and UCEC. The HNSC box plot shows higher LINC02477 RNA expression in tumor versus normal tissue (log2 FC = +0.148, t-test p < 0.001).
This table shows molecular features associated with LINC02477 in patient tissues and cancer cell lines. In patient samples, LINC02477 shows the broadest associations at the RNA and protein expression levels, with PDAC recurring as the lineage with the largest associated feature set.
