SCN1A-AS1

Across TCGA patient cohorts, SCN1A-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,935 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCN1A-AS1-associated proteins across cancer lineages are MAP1B_S992, ZFHX3_S2795, and SPAST_S268. Each is linked with SCN1A-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCN1A-AS1-to-partner and partner-to-SCN1A-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCN1A-AS1 versus MAP1B_S992 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN1A-AS1→partner) and Y-score (partner→SCN1A-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP1B_S992 →	+0.863	+0.852	<.001	<.001	3	4
CCRCC	ZFHX3_S2795 →	+0.405	+0.721	<.001	<.001	3	3
HNSC	SPAST_S268 →	+0.873	+0.869	.004	<.001	3	3
LSCC	ATP2B1 →	+0.661	+1.009	<.001	<.001	3	3
HNSC	UGDH →	+0.967	+0.738	<.001	<.001	3	3
HNSC	RAB22A →	-0.256	-0.565	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,935 associations by consensus.

SCN1A-AS1 vs MAP1B_S992 — LSCC

Explore this scatter interactively →