SASH1

Across TCGA cell cohorts, SASH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,045 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SASH1-associated GO terms across cancer lineages are Positive regulation of JUN kinase activity, Endosomal transport, and Lysosomal transport. Each is linked with SASH1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SASH1-to-partner and partner-to-SASH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of JUN kinase activity grouped by SASH1-low versus SASH1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SASH1→partner) and Y-score (partner→SASH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of JUN kinase activity →	+0.125	+0.875	<.001	<.001	3	11
STOMACH	Endosomal transport →	+0.086	+2.105	<.001	<.001	3	10
STOMACH	Lysosomal transport →	+0.087	+1.565	.006	.008	2	10
SKIN	Regulation of Golgi organization →	+0.084	+1.691	<.001	<.001	3	9
STOMACH	Vacuolar transport →	+0.082	+1.704	.007	.002	2	9
LUNG_NSCLC_LUAD	Regulation of JUN kinase activity →	+0.108	+1.167	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,045 associations by consensus.

Positive regulation of JUN kinase activity by SASH1 expression — OVARY

Explore this box plot interactively →