SAA3P

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SAA3P mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAA3P-associated genes across cancer lineages are pDC and Mast cells. Each is linked with SAA3P in more than 1 cancer types. Because this analysis shows association rather than direction, both SAA3P-to-partner and partner-to-SAA3P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by SAA3P-low versus SAA3P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA3P→partner) and Y-score (partner→SAA3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECpDC →+0.096+3.010<.001.02012
UCECMast cells →-0.024-2.957.010.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

pDC by SAA3P expression — UCEC

Box plot of pDC in SAA3P-low vs SAA3P-high samples in UCEC.

Explore this box plot interactively →

Exploration