Across TCGA pan-cancer cohorts, SAA3P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SAA3P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SAA3P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SAA3P is over-expressed in tumor.
LUSC and STAD are the cancer types where SAA3P tumor–normal differential expression is most reproducible.