SAA3P

Across TCGA pan-cancer cohorts, SAA3P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated SAA3P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher SAA3P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SAA3P expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

UVM, TGCT, and KICH are the cancer types where SAA3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.297	0.746	<.001	96	view →
TGCT	DFS	Tertile	II,III,IV	0.339	0.955	<.001	72	view →
KICH	OS	Tertile	All	0.082	0.877	<.001	63	view →
KIRC	OS	Tertile	All	0.784	0.884	.002	48	view →
COAD	DFS	Tertile	III,IV	0.273	0.671	<.001	48	view →
UCS	OS	Tertile	II,III,IV	0.889	0.393	.009	48	view →
SKCM	OS	Quartile	III,IV	0.543	0.356	.014	35	view →
PCPG	DFS	Tertile	All	0.527	0.908	<.001	30	view →
BRCA	DFS	Tertile	All	0.651	0.510	.029	21	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
ESCA	OS	Tertile	III,IV	0.729	0.358	.035	18	view →
THYM	OS	Tertile	III,IV	0.212	1.000	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

SAA3P–UVM (OS)

Open the UVM breakdown →