RWDD2A

Across TCGA patient cohorts, RWDD2A mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RWDD2A-associated genes across cancer lineages are MIR6775, MDH1P2, and RN7SL849P. Each is linked with RWDD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both RWDD2A-to-partner and partner-to-RWDD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6775 grouped by RWDD2A-low versus RWDD2A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RWDD2A→partner) and Y-score (partner→RWDD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6775 →	+0.778	+3.756	<.001	.001	3	1
BRCA	MDH1P2 →	+0.050	+5.175	.007	.007	3	1
BRCA	RN7SL849P →	+0.301	+5.317	<.001	.006	3	1
BRCA	RNU6-406P →	+0.366	+5.096	<.001	.008	3	1
UCEC	LINC02210-CRHR1 →	+0.096	+3.344	.005	.008	3	1
UCEC	MIR3146 →	+0.453	+3.329	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

MIR6775 by RWDD2A expression — UCEC

Explore this box plot interactively →