RWDD2A

Across TCGA pan-cancer cohorts, RWDD2A RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RWDD2A data layer compared with 3 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RWDD2A RNA is associated with better overall survival. In most high-consensus cancer types, elevated RWDD2A expression acts as an unfavorable survival marker, although some lineages such as SKCM and PAAD show a favorable association.

SKCM, PAAD, and KICH are the cancer types where RWDD2A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.331	0.221	<.001	87	view →
PAAD	OS	Median	All	0.516	0.272	<.001	67	view →
KICH	DFS	Tertile	III,IV	0.363	1.000	.001	47	view →
HNSC	OS	Tertile	III,IV	0.760	0.584	.005	42	view →
LGG	DFS	Median	All	0.491	0.288	<.001	41	view →
OV	OS	Quartile	III,IV	0.420	0.275	.002	38	view →
LUAD	OS	Quartile	III,IV	0.571	0.164	.008	26	view →
COAD	DFS	Median	II,III,IV	0.558	0.360	.001	23	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	21	view →
READ	DFS	Tertile	II,III,IV	0.643	0.286	.007	18	view →
SCLC	OS	Tertile	III,IV	0.392	0.838	.020	18	view →
LIHC	DFS	Median	All	0.472	0.608	.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RWDD2A–SKCM (OS)

Open the SKCM breakdown →