RSRC1

Across TCGA patient cohorts, RSRC1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,319 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RSRC1-associated genes across cancer lineages are DKC1, SMC4, and TOPBP1. Each is linked with RSRC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RSRC1-to-partner and partner-to-RSRC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RSRC1 versus DKC1 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSRC1→partner) and Y-score (partner→RSRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DKC1 →	+0.841	+0.383	<.001	<.001	3	7
LSCC	SMC4 →	+1.018	+0.317	<.001	<.001	3	6
LSCC	TOPBP1 →	+0.908	+0.260	<.001	<.001	3	6
LSCC	RFC4 →	+1.082	+0.307	<.001	<.001	3	6
HNSC	RUVBL1 →	+0.985	+0.291	<.001	.003	3	6
HNSC	LINC01424 →	+0.674	+0.320	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,319 associations by consensus.

RSRC1 vs DKC1 — UCEC

Explore this scatter interactively →