RPUSD4

Across TCGA patient cohorts, RPUSD4 mutation is significantly associated with the RNA expression of many other genes, with 1,149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPUSD4-associated genes across cancer lineages are RN7SL498P, H3P35, and MTND4LP24. Each is linked with RPUSD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPUSD4-to-partner and partner-to-RPUSD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL498P grouped by RPUSD4-low versus RPUSD4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPUSD4→partner) and Y-score (partner→RPUSD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL498P →	+0.170	+3.684	.004	.009	3	2
BRCA	H3P35 →	+0.078	+4.298	<.001	.009	3	2
BRCA	MTND4LP24 →	+0.259	+5.281	<.001	.002	3	2
CESC	RNY4P14 →	+0.360	+6.144	<.001	.001	3	2
UCEC	SNORD116-10 →	+0.176	+3.113	.002	.006	3	2
UCEC	RNU6-366P →	+0.163	+3.003	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,149 associations by consensus.

RN7SL498P by RPUSD4 expression — LUSC

Explore this box plot interactively →