RPP38

Across TCGA patient cohorts, RPP38 mutation is significantly associated with the RNA expression of many other genes, with 1,405 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPP38-associated genes across cancer lineages are RNU6-1155P, RN7SKP214, and FAM27B. Each is linked with RPP38 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPP38-to-partner and partner-to-RPP38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1155P grouped by RPP38-low versus RPP38-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP38→partner) and Y-score (partner→RPP38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1155P →	+0.093	+4.060	.009	.006	3	2
UCEC	RN7SKP214 →	+0.193	+2.334	.002	<.001	3	2
UCEC	FAM27B →	+0.064	+3.132	<.001	.005	3	2
SKCM	CDRT15P7 →	+0.056	+4.614	<.001	.006	3	2
LUAD	MIR6879 →	+0.787	+7.930	<.001	.008	3	2
PRAD	TRAJ40 →	+0.631	+5.109	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,405 associations by consensus.

RNU6-1155P by RPP38 expression — UCEC

Explore this box plot interactively →