Q-omics provides the consensus-scored FAM27B profile across patient tissues and cancer cell-line models. FAM27B expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in LIHC. Additionally, FAM27B RNA expression shows 8,032 significant protein co-abundance associations, with the highest sampling consensus in BRCA. Together, these results highlight LIHC, and BRCA as cancer lineages where FAM27B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes FAM27B survival associations across molecular data types. FAM27B RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

FAM27B data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	LIHC (108)	view →

This table ranks reproducible FAM27B RNA expression–survival associations across cancer types. High FAM27B expression shows unfavorable associations in LIHC, BRCA, ACC and MESO, but favorable associations in STAD and OV. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for FAM27B RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.051	0.777	<.001	108	view →
BRCA	OS	Tertile	All	0.142	0.580	<.001	72	view →
STAD	OS	Tertile	III,IV	0.799	0.327	.002	46	view →
OV	OS	Tertile	All	0.453	0.299	.006	30	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
MESO	DFS	Tertile	All	0.098	0.366	.039	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

FAM27B-LIHC (OS)

Kaplan–Meier survival curve for FAM27B RNA expression in LIHC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with FAM27B in patient tissues and cancer cell lines. In patient samples, FAM27B shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	8,032	BRCA (2643)	view →
RNA	2,218	UCEC (907)	view →