FAM27B

Across TCGA patient cohorts, FAM27B RNA expression is significantly associated with the protein abundance of many other proteins, with 8,032 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM27B-associated proteins across cancer lineages are RABGEF1, CRYL1, and ACADS. Each is linked with FAM27B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM27B-to-partner and partner-to-FAM27B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM27B versus RABGEF1 in BRCA, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM27B→partner) and Y-score (partner→FAM27B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RABGEF1 →	-0.242	-0.976	.003	.002	3	3
GBM	CRYL1 →	-0.367	-0.556	<.001	<.001	3	3
BRCA	ACADS →	-0.628	-1.115	<.001	<.001	3	3
UCEC	SPATA18_S274 →	+1.313	+1.142	.001	<.001	3	3
OV	DNAJA1 →	+0.265	+0.871	.001	.002	3	3
UCEC	MAP1A →	+0.618	+1.223	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,032 associations by consensus.

FAM27B vs RABGEF1 — BRCA

Explore this scatter interactively →