RPL37

Across TCGA patient cohorts, RPL37 mutation is significantly associated with the RNA expression of many other genes, with 144 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RPL37-associated genes across cancer lineages are RNU6-66P, RNU6-593P, and LINC02621. Each is linked with RPL37 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL37-to-partner and partner-to-RPL37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-66P grouped by RPL37-low versus RPL37-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL37→partner) and Y-score (partner→RPL37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-66P →	+0.369	+4.335	<.001	.007	3	2
UCEC	RNU6-593P →	+0.628	+3.957	.008	.003	3	2
UCEC	LINC02621 →	+0.227	+3.581	.004	.004	3	2
READ	IL3 →	+0.083	+5.421	<.001	.005	3	1
READ	RNU6-59P →	+0.381	+5.925	<.001	.002	3	1
READ	MIR1302-5 →	+0.500	+7.276	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 144 associations by consensus.

RNU6-66P by RPL37 expression — UCEC

Explore this box plot interactively →