RPL37

Across TCGA pan-cancer cohorts, RPL37 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RPL37’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL37 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where RPL37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	+1.161	<.001	12	view →
COAD	Female	All	+1.022	<.001	10	view →
LIHC	Female	II,III,IV	+1.103	<.001	9	view →
KIRP	All	III,IV	+0.916	<.001	8	view →
LUAD	Male	All	+0.743	<.001	8	view →
HNSC	Male	All	+0.587	<.001	8	view →
BRCA	Female	II,III,IV	−0.364	<.001	6	view →
CHOL	Male	All	+2.013	<.001	5	view →
LUSC	Male	II,III,IV	+1.070	<.001	5	view →
READ	All	All	+0.876	<.001	5	view →
STAD	All	All	+0.479	.004	4	view →
PRAD	All	All	+0.378	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RPL37–KIRC

Open the KIRC breakdown →