RPL30

Across TCGA patient cohorts, RPL30 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL30-associated genes across cancer lineages are RNU6-626P, H2BL1P, and RNU7-176P. Each is linked with RPL30 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL30-to-partner and partner-to-RPL30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-626P grouped by RPL30-low versus RPL30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL30→partner) and Y-score (partner→RPL30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-626P →	+0.593	+6.123	<.001	.002	3	2
COAD	H2BL1P →	+0.094	+7.741	<.001	.009	3	1
COAD	RNU7-176P →	+0.537	+7.741	<.001	.009	3	1
COAD	RNU7-105P →	+0.441	+7.741	<.001	.009	3	1
UCEC	LINC02563 →	+0.339	+5.420	<.001	.005	3	1
UCEC	RNU6-391P →	+0.851	+6.027	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

RNU6-626P by RPL30 expression — UCEC

Explore this box plot interactively →