H2BL1P

Q-omics provides the consensus-scored H2BL1P profile across patient tissues and cancer cell-line models. H2BL1P expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in SKCM. Additionally, H2BL1P RNA expression shows 6,018 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SKCM, and STAD as cancer lineages where H2BL1P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes H2BL1P survival associations across molecular data types. H2BL1P RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

H2BL1P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	SKCM (54)	view →

This table ranks reproducible H2BL1P RNA expression–survival associations across cancer types. High H2BL1P expression shows unfavorable associations in SKCM, BRCA, UCEC, UVM, TGCT and THYM. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for H2BL1P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.074	0.739	<.001	54	view →
BRCA	OS	Tertile	IV	0.233	0.755	.038	36	view →
UCEC	DFS	Tertile	All	0.670	0.845	.002	36	view →
UVM	OS	Tertile	All	0.248	0.769	.007	36	view →
TGCT	OS	Tertile	All	0.542	0.968	.002	18	view →
THYM	OS	Tertile	All	0.381	0.878	.017	12	view →

Pink = unfavorable, green = favorable. all 8 lineages →

H2BL1P-SKCM (DFS)

Explore this curve interactively →