RPL30

Across TCGA pan-cancer cohorts, RPL30 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RPL30’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL30 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL30 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where RPL30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+1.094	<.001	12	view →
COAD	Male	III,IV	+0.860	<.001	10	view →
LIHC	Male	II,III,IV	+1.487	<.001	9	view →
KIRP	All	III,IV	+0.836	<.001	8	view →
HNSC	All	IV	+0.577	<.001	8	view →
CHOL	Male	All	+1.671	<.001	5	view →
LUSC	Male	II,III,IV	+0.593	<.001	5	view →
LUAD	All	All	+0.357	<.001	4	view →
STAD	All	II,III,IV	+0.477	.010	3	view →
KICH	Female	All	−0.783	.002	2	view →
UCEC	All	All	−0.466	.035	2	view →
READ	All	All	+0.613	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RPL30–KIRC

Open the KIRC breakdown →