RPGRIP1L

Across TCGA patient cohorts, RPGRIP1L RNA expression is significantly associated with the protein abundance of many other proteins, with 16,094 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPGRIP1L-associated proteins across cancer lineages are FTO, PLCG2, and CEP41. Each is linked with RPGRIP1L in more than 5 cancer types. Because this analysis shows association rather than direction, both RPGRIP1L-to-partner and partner-to-RPGRIP1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPGRIP1L versus FTO in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPGRIP1L→partner) and Y-score (partner→RPGRIP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FTO →	+0.432	+0.515	<.001	<.001	3	6
GBM	PLCG2 →	-0.495	-0.546	<.001	<.001	3	5
UCEC	CEP41 →	+0.436	+0.530	<.001	<.001	3	5
GBM	CFDP1 →	+0.355	+0.434	<.001	<.001	3	5
GBM	CIAPIN1 →	+0.299	+0.588	<.001	<.001	3	5
LSCC	PTK2B_S375 →	-0.324	-0.405	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,094 associations by consensus.

RPGRIP1L vs FTO — GBM

Explore this scatter interactively →