Q-omics provides the consensus-scored RNU7-49P profile across patient tissues and cancer cell-line models. RNU7-49P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, RNU7-49P is differentially expressed in 5, with the highest sampling consensus in KIRC. Additionally, RNU7-49P RNA expression shows 15,946 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight SKCM, KIRC, and UVM as cancer lineages where RNU7-49P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU7-49P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU7-49P survival associations across molecular data types. RNU7-49P RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU7-49P RNA expression–survival associations across cancer types. High RNU7-49P expression shows unfavorable associations in OV, LIHC and UVM, but favorable associations in SKCM, LUAD and BLCA. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for RNU7-49P RNA expression.
This table summarizes RNU7-49P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU7-49P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU7-49P shows higher tumor expression in KIRC, CHOL, HNSC, PRAD and LIHC. The KIRC box plot shows higher RNU7-49P RNA expression in tumor versus normal tissue (log2 FC = +0.642, t-test p < 0.001).
This table shows molecular features associated with RNU7-49P in patient tissues and cancer cell lines. In patient samples, RNU7-49P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
