Across TCGA pan-cancer cohorts, RNU7-49P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU7-49P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU7-49P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-49P is over-expressed in tumor.
KIRC, CHOL, and HNSC are the cancer types where RNU7-49P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-49P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.