RNU7-49P

Across TCGA pan-cancer cohorts, RNU7-49P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNU7-49P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU7-49P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU7-49P expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

SKCM, LUAD, and BLCA are the cancer types where RNU7-49P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Quartile	III,IV	0.640	0.249	<.001	61	view →
LUAD	OS	Quartile	II,III,IV	0.548	0.245	.001	52	view →
BLCA	OS	Median	All	0.550	0.256	<.001	48	view →
OV	DFS	Median	IV	0.284	0.560	<.001	46	view →
LIHC	DFS	Median	All	0.474	0.631	.001	39	view →
UVM	OS	Quartile	III,IV	0.286	0.810	.002	34	view →
UCEC	DFS	Median	All	0.782	0.867	.006	28	view →
ACC	DFS	Quartile	All	0.491	0.803	.005	20	view →
LAML	DFS	Quartile	All	0.702	0.272	.001	18	view →
BRCA	DFS	Tertile	III,IV	0.922	0.797	.005	17	view →
PAAD	DFS	Median	II,III,IV	0.575	0.355	.003	14	view →
COAD	OS	Median	All	0.819	0.916	.006	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RNU7-49P–SKCM (OS)

Open the SKCM breakdown →