RNU6-577P

Across TCGA patient cohorts, RNU6-577P RNA expression is significantly associated with the protein abundance of many other proteins, with 7,199 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNU6-577P-associated proteins across cancer lineages are PTPN1_S378, PURB, and PPP1R12A_S668. Each is linked with RNU6-577P in more than 2 cancer types. Because this analysis shows association rather than direction, both RNU6-577P-to-partner and partner-to-RNU6-577P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNU6-577P versus PTPN1_S378 in PDAC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-577P→partner) and Y-score (partner→RNU6-577P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PTPN1_S378 →	-0.595	-0.486	<.001	<.001	3	3
HNSC	PURB →	+0.246	+0.993	.003	<.001	3	3
BRCA	PPP1R12A_S668 →	+1.956	+1.185	<.001	.005	3	3
OV	TNN →	+0.945	+0.850	.004	.004	3	3
OV	CDC37L1 →	+0.234	+0.609	.006	.007	3	3
LSCC	CALU_S44 →	-2.585	-1.517	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,199 associations by consensus.

RNU6-577P vs PTPN1_S378 — PDAC

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