RNU6-577P

Across TCGA pan-cancer cohorts, RNU6-577P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-577P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-577P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-577P expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRC show a favorable association.

UVM, CHOL, and BLCA are the cancer types where RNU6-577P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.430	0.873	.001	78	view →
CHOL	DFS	Tertile	III,IV	0.094	0.562	.004	52	view →
BLCA	OS	Tertile	IV	0.923	0.472	.017	25	view →
KIRC	DFS	Quartile	All	0.889	0.691	.005	22	view →
READ	DFS	Tertile	IV	0.179	0.936	.010	21	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	18	view →
UCEC	DFS	Tertile	IV	0.279	0.719	.013	18	view →
LIHC	DFS	Tertile	All	0.452	0.596	.007	13	view →
STAD	OS	Quartile	III,IV	0.324	0.598	.015	12	view →
KIRP	DFS	Median	IV	0.593	0.039	.014	12	view →
LGG	DFS	Quartile	All	0.748	0.871	.003	10	view →
THCA	DFS	Quartile	IV	0.663	0.911	.024	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU6-577P–UVM (OS)

Open the UVM breakdown →