RNU6-375P

Across TCGA patient cohorts, RNU6-375P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,642 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-375P-associated GO terms across cancer lineages are Regulation of RNA splicing, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Negative regulation of cellular catabolic process. Each is linked with RNU6-375P in more than 22 cancer types. Because this analysis shows association rather than direction, both RNU6-375P-to-partner and partner-to-RNU6-375P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by RNU6-375P-low versus RNU6-375P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-375P→partner) and Y-score (partner→RNU6-375P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of RNA splicing →	+0.064	+0.752	<.001	<.001	3	23
STAD	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.062	+0.746	<.001	<.001	3	22
STAD	Negative regulation of cellular catabolic process →	+0.049	+0.738	<.001	<.001	3	22
STAD	Nuclear export →	+0.062	+0.757	<.001	<.001	3	22
STAD	Regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.060	+0.741	<.001	<.001	3	22
ESCA	RNA export from nucleus →	+0.091	+0.825	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,642 associations by consensus.

Regulation of RNA splicing by RNU6-375P expression — STAD

Explore this box plot interactively →