RNU6-375P

Across TCGA pan-cancer cohorts, RNU6-375P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-375P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU6-375P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-375P is over-expressed in tumor, although a few such as LUAD and KIRP show the opposite, repressed pattern.

KIRC, LUAD, and KIRP are the cancer types where RNU6-375P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-375P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.193	.009	6	view →
LUAD	All	III,IV	−0.526	.029	2	view →
KIRP	All	III,IV	−0.123	.033	2	view →
CHOL	All	All	+0.500	.016	1	view →
THCA	All	All	−0.137	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RNU6-375P–KIRC

Open the KIRC breakdown →