RNU6-375P

Across TCGA pan-cancer cohorts, RNU6-375P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-375P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-375P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-375P expression acts as an unfavorable survival marker, although some lineages such as BRCA and ESCA show a favorable association.

KIRC, BRCA, and OV are the cancer types where RNU6-375P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.538	0.684	<.001	69	view →
BRCA	DFS	Tertile	III,IV	0.890	0.749	.008	36	view →
OV	OS	Tertile	IV	0.542	0.805	.002	30	view →
HNSC	DFS	Tertile	II,III,IV	0.316	0.585	.004	27	view →
ESCA	OS	Tertile	III,IV	0.687	0.308	.006	18	view →
DLBC	DFS	Tertile	III,IV	0.137	0.761	.014	18	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	18	view →
ACC	DFS	Tertile	All	0.117	0.583	.001	18	view →
PAAD	OS	Tertile	All	0.764	0.416	.014	15	view →
MESO	OS	Tertile	IV	0.266	0.608	.044	9	view →
THCA	OS	Tertile	IV	0.751	1.000	.014	9	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-375P–KIRC (OS)

Open the KIRC breakdown →