RNU6-1046P

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNU6-1046P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,411 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-1046P-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Cellular respiration, and Positive regulation of chromosome organization. Each is linked with RNU6-1046P in more than 13 cancer types. Because this analysis shows association rather than direction, both RNU6-1046P-to-partner and partner-to-RNU6-1046P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA splicing grouped by RNU6-1046P-low versus RNU6-1046P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-1046P→partner) and Y-score (partner→RNU6-1046P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCANegative regulation of RNA splicing →+0.071+0.708<.001<.001314
ESCACellular respiration →+0.069+0.770<.001<.001313
ESCAPositive regulation of chromosome organization →+0.064+0.676<.001<.001312
ESCANegative regulation of mRNA processing →+0.062+0.564<.001<.001312
ESCAPositive regulation of binding →+0.049+0.481.001<.001312
ESCARegulation of proteasomal protein catabolic process →+0.064+0.639<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,411 associations by consensus.

Negative regulation of RNA splicing by RNU6-1046P expression — ESCA

Box plot of Negative regulation of RNA splicing in RNU6-1046P-low vs RNU6-1046P-high samples in ESCA.

Explore this box plot interactively →

Exploration