RNU6-1046P

associated omics data
RNA, U6 small nuclear 1046, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-1046P profile across patient tissues and cancer cell-line models. RNU6-1046P expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, RNU6-1046P is differentially expressed in 3, with the highest sampling consensus in KIRC. Additionally, RNU6-1046P RNA expression shows 6,411 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BLCA, KIRC, and STAD as cancer lineages where RNU6-1046P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-1046P survival associations across molecular data types. RNU6-1046P RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-1046P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier15BLCA (96)view →
This table ranks reproducible RNU6-1046P RNA expression–survival associations across cancer types. High RNU6-1046P expression shows unfavorable associations in UCS, KIRC, ACC, CESC and HNSC, but favorable associations in BLCA. The BLCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify BLCA as the clearest survival context for RNU6-1046P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSTertileIII,IV0.7720.532.00196view →
UCSDFSTertileII,III,IV0.1680.493.00772view →
KIRCDFSTertileII,III,IV0.3380.584<.00166view →
ACCOSTertileII,III,IV0.1220.707<.00139view →
CESCOSTertileIV0.2630.651.01336view →
HNSCOSTertileIII,IV0.2940.694.00336view →
Pink = unfavorable, green = favorable. all 15 lineages →

RNU6-1046P-BLCA (DFS)

Kaplan–Meier survival curve for RNU6-1046P RNA expression in BLCA: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes RNU6-1046P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in KIRC for RNA.
RNU6-1046P data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot3KIRC (8)view →
This table ranks reproducible tumor–normal expression differences for RNU6-1046P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-1046P shows lower tumor expression in KIRC and LUAD and higher tumor expression in UCEC. The KIRC box plot shows higher RNU6-1046P RNA expression in normal versus tumor tissue (log2 FC = −0.119, t-test p < 0.001).
LineageGenderStageFold-changepSampling consensus
KIRCAllAll−0.119<.0018view →
LUADFemaleIII,IV−0.416.0232view →
UCECAllAll+0.308.0312view →
Green = repressed in tumor. all 3 lineages →

RNU6-1046P-KIRC

Tumor-vs-normal expression box plot for RNU6-1046P in KIRC.

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Cross-omics associations

This table shows molecular features associated with RNU6-1046P in patient tissues and cancer cell lines. In patient samples, RNU6-1046P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
Function (RNA)6,411STAD (5672)view →
Protein (mass-spec)4,492LUAD (2273)view →