RNU6-1046P

Across TCGA pan-cancer cohorts, RNU6-1046P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6-1046P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU6-1046P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1046P is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and UCEC are the cancer types where RNU6-1046P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1046P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.119	<.001	8	view →
LUAD	Female	III,IV	−0.416	.023	2	view →
UCEC	All	All	+0.308	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU6-1046P–KIRC

Open the KIRC breakdown →